Peyronie’s Disease Treatments For Men

Men with small plaques, not very curved penis, pain, and problems with sex may need treatment, and we can offer them an effective choice.

What is Peyronie’s disease?

Peyronie’s disease is a disorder in which scar NIH external link tissue, called plaque, forms under the skin of the penis—the male organ used for urination and sex.

The plaque builds up inside the penis, in the thick elastic membrane called the tunica albuginea. The tunica albuginea helps keep the penis stiff during an erection. The plaque can develop anywhere along the penis.

As it develops, the plaque pulls on the surrounding tissues and causes the penis to curve or bend, usually during an erection. Curves in the penis can make erections painful and may make sexual intercourse painful, difficult, or impossible.

Read about: ED Treatments

What are the complications of Peyronie’s disease?

  • Complications of Peyronie’s disease may include
  • the inability to have sexual intercourse due to penile curvature
  • emotional distress, depression, or anxiety about sexual abilities or the appearance of the penis
  • stress in a relationship with a sexual partner
  • problems fathering a child because intercourse is difficult

What are the signs and symptoms of Peyronie’s disease?

The signs and symptoms of Peyronie’s disease may include:

  • hard lumps on one or more sides of the penis
  • pain during sexual intercourse or during an erection
  • a curve in the penis with or without an erection
  • changes in the shape of the penis, such as narrowing or shortening
  • ED

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These may develop slowly or appear quickly and can be mild to severe. In many cases, the pain decreases over time, although the curve in the penis may remain. Problems with intercourse or ED can occur during either phase.

What causes Peyronie’s disease?

Medical experts do not know the exact cause of Peyronie’s disease but believe that it may be the result of

  • acute or chronic injury to the penis
  • autoimmune disease

Peyronie’s disease is not contagious or caused by any known transmittable disease.


Your health care provider may be able to tell if you have Peyronie’s disease with only a physical exam. The hard plaques can most often be felt whether the penis is stiff or not. To check how the penis curves, your health care provider may inject a drug into your penis to make it stiff and may take pictures to study. In some cases, dynamic ultrasound, which uses sound waves to get a picture of what is in your body, is used to see where the plaque is, check for calcium buildup, and show how the blood flows in your penis.


Treatment recommendations for Peyronie’s disease depend on how long it’s been since you began having symptoms.

  • Acute phase. You have penile pain or changes in curvature or length or a deformity of the penis. The acute phase happens early in the disease and may last only two to four weeks but sometimes lasts for up to a year or longer.
  • Chronic phase. Your symptoms are stable, and you have no penile pain or changes in curvature, length, or deformity of the penis. The chronic phase happens later in the disease and generally occurs around three to 12 months after symptoms begin.

For the acute phase of the disease, treatments range from:

  • Recommended. When used early in the disease process, penile traction therapy prevents length loss and minimizes the extent of curvature that occurs.
  • Optional. Medical and injection therapies are optional in this phase, with some more effective than others.
  • Not recommended. Surgery isn’t recommended until the disease stabilizes, to avoid the need for repeat surgery.

For the chronic phase of the disease, several potential treatments are available. They may be done alone or in combination:

  • Watchful waiting
  • PRP (P-Shot)
  • Regenerative Therapy
  • Surgery

If you have other symptoms that are not often seen with Peyronie’s disease, such as external bleeding, trouble peeing, or penile pain that lasts for a long time, your health care provider may take a sample of the tissue (biopsy) for further study. Use our contact form to learn more.